MMP7 and pancreatic ductal adenocarcinoma: MMP7 is overexpressed in pancreatic intraepithelial neoplasia (PanINs) and pancreatic ductal adenocarcinoma (PDA) and has been found to promote the initiation and progression of PDA [33,34,35]; it is also correlated with the reduced survival and distant metastasis of PDA [35,36].