Their clinical symptoms can be divided into two categories: first, excessive PRL secreted by tumors leading to sexual dysfunction in men and menstrual disorders including amenorrhea, infertility, lactation, and other symptoms in women; and second, mass compression effect caused by the large tumor size, leading to headache, nausea and vomiting, visual impairment, and cranial nerve dysfunction [2]. This evidence concerns the gene PRL and neoplasm.