CXCL8 and infection: Similarly, a trend of increases in the production of IL-8 was detected at 6 h post infection (86.31 pg/mg ± 15.93), which later significantly peaked at 24 h post infection (202.21 pg/mg ± 57.96, p = 0.0003) as compared to sham non-infected rats (26.81 pg/mg ± 2.38) (F(2,12) = 17.05, p = 0.0003).