In this study, the host-selection behavior of BPH, BPH for the healthy rice plants and the BPH-damaged rice plants was measured under ambient and elevated CO2, as well as the expression levels of OBPs (including OPB1, OBP2 and OBP3) and CSPs (including CSP3, CSP8 and CSP10) in BPH, and the emission of VOCs from the healthy and BPH-damaged rice plants, in order to make clear how plant VOCs from rice plants affect the host-selection behavior of BPH in responding to elevated CO2. This evidence concerns the gene KIF22 and benign prostatic hyperplasia.