Similarly, upregulated ICAM1 in the one-carbon metabolism pathway through an integrated analysis is an important finding because its upregulation reduces ovarian cancer cell growth [59]; at the same time, it needs further investigation because our transcriptome data suggested high inflammatory responses, in the forms of upregulated TLRs, cytokines, Fas, and Fasl [59]. This evidence concerns the gene ICAM1 and ovarian carcinoma.