TGFB1 and neoplasm: MSCs can stimulate tumor neoangiogenesis through the production and secretion of multiple angiogenesis factors such as ANGs, EGF, galectin-1 (GAL-1), IGF-1, keratinocyte growth factor (KGF), VEGF, TGF-β, IL-6, and macrophage inflammatory protein (MIP) 2.