In addition, Ki-67 can be used in combination with other markers such as MCM-2, survivin, B7-H1, geminin, carbonic anhydrase, IX, gelsolin, MIB-1, and phosphorylated S6 protein, and the interaction between white (pS6) and vimentin affects the prognosis of renal cancer. The gene discussed is VIM; the disease is renal carcinoma.