Regarding the relationship between circulating collagen turnover biomarkers and the severity of HF, Gal3 and PICP were inversely correlated with LVEF (r2 = −0.58, p < 0.0001; r2 = −0.39, p < 0.0001) and NYHA class ≥III (r2 = −0.56, p < 0.0001; r2 = −0.39, p < 0.0001), and directly correlated with NT-proBNP (r2 = 0.49; p < 0.0001; r2 = 0.32; p < 0.0001) and CCP (r2 = 0.41; p < 0.0001; r2 = 0.38; p < 0.0001) levels. Here, NPPB is linked to hydrops fetalis.