Liu et al. [32], in a systematic review and meta-analysis including 45 studies and 5654 patients, showed an acceptable level of sensitivity of 75% (95% CI: 69–79%) but a weak level of specificity of 67% (95% CI: 58–74%) for the ability of CRP to differentiate patients with sepsis vs. non-infectious inflammatory state/disorders. This evidence concerns the gene CRP and Sepsis.