Furthermore, another study indicates that NEAT1 inhibits the LPS-induced progression of sepsis in RAW264.7 cells by modulating the miR-31-5p/POU2F1 axis [98], suggesting that NEAT1, which also positively correlates with Th1 and Th17 levels [99], will be a potential target for clinical treatment of sepsis-induced organ damage. This evidence concerns the gene POU2F1 and Sepsis.