According to the histological grades of squamous cell carcinoma based on tumor differentiation, the positive staining for p40 was observed in 15/17 (88.23%) cases of well-differentiated squamous cell carcinoma (WDSCC; Figure 1B), 17/21 cases (80.95%) of moderately differentiated squamous cell carcinoma (MDSCC; Figure 1C) and 7/8 cases (87.50%) of PDSCC (Figure 1D) (Table 3). The gene discussed is TP63; the disease is squamous cell carcinoma.