A study involving a proteomics-based approach identified numerous protein markers, namely prothymosin alpha (PTMA), S100A7, 14-3-3ζ, 14-3-3δ, hnRNPD, and hnRNPK, used for distinguishing between normal mucosa, dysplasia, and oral cancer [26,27]. Here, PTMA is linked to lip and oral cavity carcinoma.