There is a strong association observed between the ACE2–II and ACE2–(DI+DD) genotypes in the dominant inheritance model and leads to increased CAD susceptibility with an OR = 2.86, (95%) CI (1.27–6.41), RR= 1.52(1.1850 to 1.9593), and p < 0.010 (Table 4). This evidence concerns the gene ACE2 and coronary artery disorder.