To determine whether global transcriptome analysis would demarcate these HE populations, we next used gene expression profiles from hPSC progenies from several sources and procedures, including 7TF overexpression [30,32,47], and compared these to publicly available datasets of primitive hematopoietic populations enriched for HSC/HPCs (CD45+CD34+CD38−), including BM, MPB, CB, and fetal blood (FB) sources (Figure 1F). This evidence concerns the gene CD38 and hereditary elliptocytosis.