MYC and colorectal carcinoma: Interestingly, in a recent study conducted by Miao and Wang (2019) [139], it has been reported that hPRPS2 promotes the movement and invasion of colorectal cancer cells (CRC), suggesting that the upregulation of PRPS2 observed in CRC was induced by the MYC proto-oncogene, thus implicating PRPS2 in CRC metastasis.