However, the inhibition of MLKL with its inhibitor (necrosulfonamide–CAS 432531-71-0–Calbiochem) at different doses did not impact AKI-induced increases in cGAS and STING or reductions in Mitofilin levels observed after AKI compared to the sham group (Figure 10C). Here, STING1 is linked to acute kidney injury.