ITGAM and neoplasm: In support of this, adoptive transfer of large numbers of CD11b+ and GR1+ leukocytes from tumor-bearing mice (which would include inflammatory monocytes, neutrophils, and gMDSCs [41]) or CD11b+ and GR1+ cells from healthy mice (which would confer inflammatory monocytes and neutrophils, but few gMDSCs) similarly activated an acute-phase protein response [42].