In Burkitt’s lymphoma (BL) cells that have a c-MYC chromosomal translocation to one of the immunoglobulin (IG) loci on chromosomes 2, 14, or 22, the transcription of a c-MYC proto-oncogene is characterized by preferential transcription from the c-MYC promoter P1 [11]. Here, MYC is linked to Burkitt lymphoma.