This approach is also intriguing in light of our recent demonstration that high expression of the TCA cycle transferase DLST contributes to tumor development in multiple MYC-driven cancers, such as T-ALL, high-risk neuroblastoma, and triple-negative breast cancer (TNBC) [11,20,24,25,26,27,28]. This evidence concerns the gene MYC and acute lymphoblastic leukemia.