We demonstrated that the expression of NR2F1 gene was higher in previously established dormant cells (D2OR murine breast cancer cells) [44] compared to the proliferative cells (D2A1 cells) in 3D cultures, and the expression of RARB and TGFB1 genes are higher in dormant cells compared to the proliferative cells in both 2D and 3D cultures (Figure 1A, all p < 0.02). The gene discussed is RARB; the disease is breast carcinoma.