DDIT3 and serous adenocarcinoma: It is interesting to note that the gene expression analysis of high-grade serous carcinomas from The Cancer Genome Atlas datasets, available from UALCAN [40], cbioportal [41], and KM plotter [42], indicates relatively higher expression of HRI (EIF2AK1) compared to PERK (EIF2AK3) or PKR (EIF2AK2) and higher expression of pro-survival gene GRP78 compared to pro-apoptotic gene CHOP (Figure S14A).