TP53 and Anxiety: We found a significant difference in anxiety (mean HADS-A) between Day 1 (T1) and Day 120 (T3) in the experimental groups (E1/T1 vs. E1/T3, p < 0.0001; E2/T1 vs. E2/T3, p < 0.0113), suggesting that anxiety is of short duration based on the result disclosure of a positive test for TP53 p.R337H (Figure 2).