RRM2 and cancer: Compared with paired para-cancerous samples in TCGA, RRM2 expression also increased in the paired pan-cancer samples of 16 types of cancers: BLCA, BRCA, CHOL, COAD, ESCA, HNSC, KIRC, KIRP, LIHC, LUAD, LUSC, PRAD, READ, STAD, THCA, and UCEC (Figure 1C).