In a cohort of patients with ACC-induced HF, doublings of NT-proBNP and PICP were associated with lower LVEF (−2.80% [95%CI: −4.44 to −1.17], r = −0.510, p = 0.001 and −10.5% [95%CI: −17.4 to −3.66], r = −0.469, p = 0.004, respectively). Here, NPPB is linked to hydrops fetalis.