While some authors suggest similar BRAF, NRAS, and KRAS mutational profiles in CD-associated and sporadic CRC [27], the results of a recent meta-analysis investigating both UC and CD-associated CRC described a higher prevalence of TP53 mutations and a lower prevalence of KRAS mutations in IBD-associated CRC than in sporadic CRC [28]. Here, TP53 is linked to inflammatory bowel disease.