CD8A and neoplasm: The mean percentage of CD8+ CD137+ TILs was 3.1% and varied between 0–10% (Table S5), and >5% of the CD8+ cytotoxic T-cells (CTLs) from OvCa #1, #3 and #5 (Figure 5B) co-expressed CD137, indicating their pre-exposure to tumor antigens.