As compared with the untreated control group, mice treated with 0.1 or 0.5 mg/kg CD1a x CD3ε showed significantly reduced tumor growth at both concentrations (Figure 5B) and this effect translated into a prolonged survival of animals with a median survival of 41 days in vehicle group and 62 and 63 days in mice treated with 0.1 or 0.5 mg/kg CD1a x CD3ε, respectively (Figure 5C). Here, CD3E is linked to neoplasm.