When looking across all ovarian cancer subtypes genes involved in the PI3K–Akt pathway (PTEN and PIK3CA), genes associated with the MAPK pathway (KRAS and BRAF), and other oncogenic genes (CTNNB1 and PPP2R1A) were also found to be mutated at a moderate frequency [1,192]. This evidence concerns the gene PIK3CA and ovarian carcinoma.