The presence of CD103+CD39+CD8+ TRM cells responding to cognate antigens in CRLM (Figure 2C,D) prompted the expansion of TILs, which may increase the number of scarce tumor-reactive TILs, and enabled us to address whether expanded TILs would accumulate in the autologous tumor as TRM cells to control tumor growth. The gene discussed is CD8A; the disease is neoplasm.