Interestingly, Chin et al. reported distinctive sets of proteins secreted by Schizosaccharomyces pombe in the stool samples of CRC patients, and four proteins (SWR1 complex bromodomain subunit bdf1, structural maintenance of chromosomes protein 5, DNA repair protein rhp57, and uncharacterized WD repeat-containing protein C16H5.13) were closely linked with advanced CRC [24]. Here, PROS1 is linked to colorectal carcinoma.