Chen et al. showed that Saccharomyces boulardii CNCM I-745, a probiotic microorganism belonging to the Saccharomyces cerevisiae species [140], inhibited the epidermal growth factor receptor (EGFR)–MAPK/ERK kinase (MEK)–ERK signaling network and pro-apoptotic actions in tumor cells by suppressing Akt, a central actor of the cell cycle, thereby regulating the inflammatory responses and suppressing the gut cancer expansion [116]. Here, EGFR is linked to neoplasm.