In addition, microbiome analysis of various types of breast cancer samples, classified based on the receptors expressed on their surfaces, including estrogen receptor-positive (ER+), Her2 receptor-positive (HR+) triple positive (TP; estrogen, progesterone, and Her2 receptor-positive), and triple-negative (TN; estrogen, progesterone and Her2 receptor negative) [98] showed the highest fungal diversity in ER+ samples; and HR+ samples had the least fungal diversity. This evidence concerns the gene ESR1 and breast cancer.