On the other hand, TEX from day 7 or from 4–6 weeks after PDT were enriched in E-cadherin and restored epithelial morphology and EpCAM expression in tumor cells, reduced the expression of mesenchymal genes and inhibited proliferation, migration and invasion, suggesting that PDT promotes the transition from a mesenchymal to an epithelial tumor phenotype mediated by TEX [96]. Here, TEX46 is linked to neoplasm.