The glycolysis and the expression of its related genes (e.g., HIF1α, HIF1β, PGK1, LDHA, and MCT4) are attenuated in JMJD2D-deficient CRC cells, suggesting that JMJD2D can regulate glycolysis via the HIF1 signaling pathway [65]. Here, KDM4D is linked to colorectal carcinoma.