WEE1 and endometrial cancer: In cells, DAG, PA and PI(4,5)P2, as lipid second messengers, play an important role in regulating several signal transduction proteins [39] that, in turn, are linked to the regulation of a broad diversity of functions, including the activation of protein kinases, the activation of ion channels and cytoskeletal reorganisation, among several others [38,39,40], which can promote endometrial cancer progression.