FBXW7 and B-cell chronic lymphocytic leukemia: Finally, FBXW7 and BTG1 (BTG anti-proliferation factor 1) are linked to chromosomal translocation in B-cell chronic lymphocytic leukemia [50,51], and RORA (RAR related orphan receptor A) has an impact on angiogenesis (GO:0001525) and is crucial for the development of type 2 innate lymphoid cells and cytokine production [52,53].