To target the K-Ras mutated cells, FA-functionalized lipid (FA-DODAB/DOPE) was coated onto G@AuNS (rGADA) to deliver the G12V (glycine to valine mutation of the K-Ras oncogene on codon 12) mutant anticancer K-Ras gene plasmid (KrasI) for the pancreatic cancer gene. The gene discussed is KRAS; the disease is pancreatic neoplasm.