There were two more articles that compared the subtypes of BD with the SBD group (subthreshold bipolar disorder: more than 2-days but less than 4-days duration of hypomania) and found differences in the levels of inflammatory mediators (IL-1ß, IL-6, IL-8) and BDNF (45, 46 in Table 1). The gene discussed is IL1B; the disease is bipolar disorder.