For the study purpose to elucidate POAG and SG pathogenesis in detail, several in vitro cell cultures using human TM (HTM) have recently been utilized in conjunction with TGF-β2 and dexamethasone (DEX) to establish suitable models replicating glaucomatous TM properties [8,9,10,11]. Here, TGFB2 is linked to open-angle glaucoma.