The analysis revealed that each histopathological subtype of renal cell carcinoma is characterized by a specific p53 mutation profile or at least distinct positions in Tp53/p53 which are mutated at a higher rate (Figure 3B–E); however, there is a small amount of research focusing on the analysis of the p53 status in renal cell carcinoma patients, and therefore, there is not enough data that would give a complete picture of the mutation pattern of Tp53/p53 in this particular cancer. Here, TP53 is linked to hereditary clear cell renal cell carcinoma.