Increased levels of neuroaxonal damage markers (neurofilament light chain (NFL) and total tau protein (T-tau)) have been found in patients with both paraneoplastic and non-paraneoplastic autoimmune syndromes [5,6], as well as in other neuroinflammatory conditions, such as myelin oligodendrocyte glycoprotein antibody disorders [7] and multiple sclerosis [8,9]. Here, MAPT is linked to multiple sclerosis.