In blood vessels probed with CD31 (Figure 4B,E,H) or tomato lectin (Figure 4K,N,Q) (Lycopersicon esculentum), characteristic markers of endothelial cells, TG2 IR (Figure 4C,F,I and L,O,R respectively) was significantly enhanced in MS lesions (Figure 4D–I) compared to the controls (Figure 4A–C,J–L), while TG2 IR was not apparent in inactive or old lesions (data not shown). This evidence concerns the gene TGM2 and myeloid sarcoma.