Within mice with EMID-induced adenomyosis, the density of S100β+ SCs reduced progressively with time (p = 1.9 × 10−5), but treatment with SP600125 or U0126 resulted in a significant increase in the density of S100β+ SCs in the EMI (p = 2.8 × 10−8 and p = 1.9 × 10−5, respectively, R2 = 0.76; Figure 2A). Here, S100B is linked to adenomyosis.