However, after Cox proportional hazards models were applied to the whole study population, adjusted for first kidney disease-related hospitalization or death according to age, electrolytes, BMI, comorbidity, lipid status, serum iron, nutritional state (albumin), dialysis clearance (Kt/V), hs-CRP, IL-2, and IL-6, serum IL-18 concentration was positively correlated with the time to first hospitalization or death (1.2166 ± 0.5010, p < 0.05, hazard ratio: 3.3757, CI: 1.2644–9.0122) in multivariate analysis. The gene discussed is IL18; the disease is kidney disorder.