TNF and COVID-19: COVID-19 has been associated with a specific immune profile: a decrease in the cluster of differentiation (CD)3+, CD4+, and CD8+ cells; natural killer cells; and B-cells; a rise in interleukin (IL)-6, IL-4, and tumor necrosis factor alpha (TNF-α); and decrease in IL-10 and interferon (IFN)-γ [2].