The effects of LDRT seem to be multifactorial, and reports in non-COVID-19 patients show that they include a decrease in polymorphonuclear cells and endothelial cells, a decrease in the expression of adhesion molecules, a decrease in the production of nitric oxide (NO), an increase the activation of apoptosis mediators, and an increase the production of IL-10 and TGF-β1 [33,34,35,36,37,38]. The gene discussed is TGFB1; the disease is COVID-19.