Trx1 is elevated in distinct pathologies with the potential as biomarker, i.e., in acute coronary syndrome (ACS) and dilated cardiomyopathy, acute phase of myocarditis, unstable angina, and myocardial infarction [191], cardiac arrest [87], sepsis [192,193,194] rheumatoid arthritis [123] and stroke [195]. This evidence concerns the gene TXN and stroke disorder.