The comparison of all time-point analysis between the control and C9ALS/FTD groups (0, 4 and 8 h of BA1 treatment) indicated a non-significant trend toward increased levels of VDAC protein (Figure 4), suggesting an increased accumulation of damaged mitochondria in C9ALS/FTD patients. The gene discussed is VDAC1; the disease is frontotemporal dementia.