Since decreased protein levels of C9orf72 have been described in central nervous system areas and in some peripheral tissues of C9ALS/FTD patients [1,2,30], and C9orf72 haploinsufficiency has been described as a molecular mechanism responsible for the disease, we firstly quantified C9orf72 protein levels in our samples. The gene discussed is C9orf72; the disease is frontotemporal dementia.