The authors used resveratrol to treat STZ-induced diabetic cardiomyopathy in mice and found that resveratrol improves dysfunctional autophagy flux through the SIRT1-FOXO1-RAB7 pathway, which may provide a new approach for the treatment of diabetic cardiomyopathy [118]. This evidence concerns the gene FOXO1 and diabetic cardiomyopathy.