The NLRP3 inflammasome increased the recruitment of CD11b+Ly6ChighLy6G− myeloid cells into tumors, and IL-1β increased the recruitment of the granulocytic fraction (CD11b+Ly6G+Ly6Clow) in the primary tumor and the monocytic fraction (CD11b+Ly6ChighLy6G−) in metastatic tumors [48]. This evidence concerns the gene ITGAM and metastatic neoplasm.