H2AX and metabolic dysfunction-associated steatotic liver disease: These comparisons confirmed that the regions with high ɣH2AX levels in steatotic IHH cells were enriched in NAFLD and alcohol-related liver disease (ARLD)-associated SNVs (Fig. 3B), whereas the regions with high ɣH2AX levels in control media IHH cells were not (Fig. 3A).