Except for NL-tau animals injected at 3 months of age, AD-tau seed-injected animals exhibited significantly decreased power in Delta, Theta-1, Theta-2, low and high gamma power bands in animals injected at 3 and 6 months of age, 1 day immediately after injection (Fig. 5a, b, Table 3a) in the hippocampus. Here, MAPT is linked to Alzheimer disease.