Concurrent with the altered coagulation, an exacerbated proinflammatory cytokine response has been observed in patients with COVID-19 (C-reactive protein, ferritin, interleukin [IL]-2, IL-6, IL-7, IL-10, interferon-gamma inducible protein 10, tumor necrosis factor-α, etc.), although the cause of this cytokine storm remains unclear. The gene discussed is TNF; the disease is COVID-19.