For instance, lncRNA MEG3 inhibits proliferation and metastasis of GC through targeting p53 signaling pathway [3]; ALKBH5 propels invasion and metastasis of GC via hampering methylation of the lncRNA NEAT1 [4]; lncRNA AK023391 facilitates tumorigenesis and invasion of GC by activating PI3K/Akt signaling pathway [5]. The gene discussed is TP53; the disease is gastric cancer.