The individual CRP SNPs associated with circulating CRP were not associated with CRC or all-cause mortality, except that for SNP rs1205, significant inverse associations were observed with CRC mortality (comparing the CT and CC genotypes with TT genotype, HR 0.54, 95% CI 0.35, 0.83 and HR 0.58, 95% CI 0.38, 0.88, respectively) and all-cause mortality (HR 0.58, 95% CI 0.40, 0.85 and 0.64, 95% CI 0.44, 0.92, respectively). Here, CRP is linked to colorectal carcinoma.